Head to head
Houston Texans v San Francisco 49ers — every meeting since 2005
Houston Texans and San Francisco 49ers have met 6 times since 2005. HOU trail the regular-season series 2-4. Against the closing spread HOU are 2-4. The highest-scoring meeting produced 45 points in 2009; the widest margin was 31.
HOU record
2-4
regular season, 2005–2025
HOU v the spread
2-4
covered–against
Highest scoring
45
combined, 2009
Widest margin
31
2013 season
Every meeting
6 games, 2005–2025HOU in the last meetings
- Last 31-2
- Last 52-3
The extremes
- Highest scoring2009 week 7 · SF 21 at HOU 2445 points
- Lowest scoring2021 week 17 · HOU 7 at SF 2330 points
- Widest margin2013 week 5 · HOU 3 at SF 3431 points
By starting quarterback
regular season, 2005–2025No meeting on file names both starting quarterbacks.
6 further pairings met once each and are left out — a list where most rows read 1-0 describes single games rather than a matchup. Every one of them is in the table above.
By head coach
regular season, 2005–2025No meeting on file names both head coaches.
6 further pairings met once each and are left out — a list where most rows read 1-0 describes single games rather than a matchup. Every one of them is in the table above.
Players, since 2021
a shorter window than aboveEverything above this line covers 2005 onwards, because that is how far the schedule and the closing lines go back. Per-player box scores start at 2021, so any figure naming a player covers the 5 seasons from 2021 and no more. The two windows are kept apart rather than blended, and neither is presented as the complete history: these clubs have played each other for far longer than this database reaches, and nothing on this page covers the seasons before 2005.
Most touchdowns
since 2021 · 2 meetings
- Mac Jones QB · SF · 1g2 TD
- Trey Lance QB · SF · 1g2 TD
- C.J. Stroud QB · HOU · 1g2 TD
- Brandin Cooks WR · HOU · 1g1 TD
- George Kittle TE · SF · 1g1 TD
- Deebo Samuel Sr. WR · SF · 1g1 TD
Most passing yards
since 2021 · 2 meetings
- C.J. Stroud QB · HOU · 1g318 yds
- Trey Lance QB · SF · 1g249 yds
- Mac Jones QB · SF · 1g193 yds
- Davis Mills QB · HOU · 1g163 yds
Most rushing yards
since 2021 · 2 meetings
- Elijah Mitchell RB · SF · 1g119 yds
- Woody Marks RB · HOU · 1g62 yds
- Nick Chubb RB · HOU · 1g56 yds
- Rex Burkhead RB · HOU · 1g47 yds
- Trey Lance QB · SF · 1g31 yds
- C.J. Stroud QB · HOU · 1g30 yds
Most receiving yards
since 2021 · 2 meetings
- Brandon Aiyuk WR · SF · 1g94 yds
- George Kittle TE · SF · 2g72 yds
- Jauan Jennings WR · SF · 2g70 yds
- Xavier Hutchinson WR · HOU · 1g69 yds
- Brandin Cooks WR · HOU · 1g66 yds
- Deebo Samuel Sr. WR · SF · 1g63 yds
