Matchup
Derrick Henry has faced the 49ers once in the regular season (2017), averaging 19 rushing yards a game.
His best against them is 19 rushing yards.
Over his last 5 games he has averaged 132.8 rushing yards.
In 2025 the 49ers allowed 93.1 rushing yards a game to RBs, 2% less than the league average of 94.9.
v SF
19
one meeting, rush yds a game
Last 5
132.8
his own form, rush yds a game
SF allow
93.1
to RBs, 2025
v league
×0.98
what they give up over average
| Game | Venue | CAR | RUSH YDS | YPC | RUSH TD | REC | REC YDS | REC TD |
|---|---|---|---|---|---|---|---|---|
| 2017 WK 15 | at SF | 7 | 19 | 2.7 | 0 | 2 | 9 | 0 |
This is what the defence allowed the whole position group, not a projection for one player. Where it disagrees with the record above, the record is the thing that actually happened.
SF allowed 93.1 rush yds a game to RBs in 2025. 11 other defences are within a comparable range — ATL, CLE, DAL, DET, GB, IND, LA, LV, PHI, PIT, TEN. Derrick Henry has played them 52 times, averaging 81.8 rush yds. His last 5 games average 132.8. This is a comparison of defences that gave up similar amounts, not a forecast of this fixture.
| Game | Venue | v SF | CAR | RUSH YDS | YPC | RUSH TD | REC | REC YDS | REC TD |
|---|---|---|---|---|---|---|---|---|---|
| 2025 WK 18 | at PIT | ×1.04 | 20 | 126 | 6.3 | 0 | 0 | 0 | 0 |
| 2025 WK 17 | at GB | ×1.08 | 36 | 216 | 6.0 | 4 | 0 | 0 | 0 |
| 2025 WK 14 | v PIT | ×1.04 | 25 | 94 | 3.8 | 0 | 1 | 8 | 0 |
| 2025 WK 11 | at CLE | ×1.05 | 18 | 103 | 5.7 | 1 | 2 | 19 | 0 |
| 2025 WK 6 | v LA | ×0.95 | 24 | 122 | 5.1 | 0 | 1 | 8 | 0 |
| 2025 WK 3 | v DET | ×0.96 | 12 | 50 | 4.2 | 1 | 1 | 7 | 0 |
| 2025 WK 2 | v CLE | ×1.05 | 11 | 23 | 2.1 | 0 | 0 | 0 | 0 |
| 2024 WK 18 | v CLE | ×1.05 | 20 | 138 | 6.9 | 2 | 2 | 23 | 0 |
They are not scheduled to meet in the 2026 regular season.